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partial TCA cycle (obligate autotrophs)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
cis-aconitate + H2O <=> isocitrate 4.2.1.3 aconitate hydratase

isocitrate + NADP+ <=> 2-oxoglutarate + CO2 + NADPH 1.1.1.286 isocitrate---homoisocitrate dehydrogenase
1.1.1.41 isocitrate dehydrogenase (NAD+)
1.1.1.42 isocitrate dehydrogenase (NADP+)



phosphate + oxaloacetate <=> phosphoenolpyruvate + HCO3- 4.1.1.31 phosphoenolpyruvate carboxylase

(S)-malate <=> fumarate + H2O 4.2.1.2 fumarate hydratase
4.2.1.34 (S)-2-methylmalate dehydratase


electron-transfer_quinone + (S)-malate <=> electron-transfer_quinol + oxaloacetate 1.1.5.4 malate dehydrogenase (quinone)

citrate <=> cis-aconitate + H2O 4.2.1.117 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
4.2.1.3 aconitate hydratase


acetyl-CoA + H2O + oxaloacetate <=> citrate + CoA + H+ 2.3.3.1 citrate (Si)-synthase
2.3.3.14 homocitrate synthase
2.3.3.16 citrate synthase (unknown stereospecificity)
2.3.3.3 citrate (Re)-synthase




electron-transfer_quinone + succinate <=> electron-transfer_quinol + fumarate 1.3.5.1 succinate dehydrogenase

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